Best ways to handle spam in Drupal?
Recently my iPod and now my iPhone has been filling with the excellent Lullabot Podcast. The podcast covers everything Drupal and I've been working back through some of the previous episodes. Episode 40 covers the top 40 Drupal projects. The list is great. I've used many of the modules and I'm now experimenting with many others.
The question I came across has to do with spam handling. I'm using the Spam module and pretty happy with it. Every once in a while something slips through and very rarely there has been the odd false positive but it has worked well overall. The podcast recommends the Akismet module. Does it work better? What sorts of experiences have people had who have tried both?